BIOCHEMICAL
ALTERATIONS IN LIVER FUNCTION AND ASSOCIATED RISK FACTORS IN SPRAY PAINTERS IN
JAFFNA
Alteration in Haemoglobin, Bilirubin and Serum ALT Level in Spray Painters in Jaffna
A REPORT ON RESEARCH PROJECT FOR THE FIRST EXAMINATION IN MEDICAL DEGREES
Alteration in Haemoglobin, Bilirubin and Serum ALT Level in Spray Painters in Jaffna
A REPORT ON RESEARCH PROJECT FOR THE FIRST EXAMINATION IN MEDICAL DEGREES
By :- J.Sanjeyan
Supervisors:-Prof. (Ms).V.
Arasaratnam, Dr. S. Balakumar, Dr. T. Kumanan & Dr. (Ms.) J.
Pradeepan
Abstract
There is evidence that the spray
paints have some cascade effect on Liver function of Spray painters. This
project was carried out to study the effect of spray paints on Liver function
of Spray painters through comparing the different parameters
such Serum Alanine transaminase (ALT), Haemoglobin Level and Serum Bilirubin of
Spray painters with the Control group. For this research project 30
Professional painters had been selected randomly Among total population of 39
spray painters who were regularly exposed to spray paints more
than 1 year in Jaffna district except islands in the period of August/September 2011. Control group, which's studied
in this project showed that the mean(SD) for the Haemoglobin Level 15.19(±1.04)
g/dl, Unconjucated bilirubin 6.05(±5.6)
µmol/l, Conjucated bilirubin 10.71(±4.52)
µmol/l, Serum
total bilirubin16.76(±6.35) µmol/l
and Serum Alanine transaminase (ALT) 17.92(±9.45) IU. However
our studies on Spray
painters showed that the mean(SD) for the Haemoglobin
Level 14.30(±1.11)
g/dl, Serum Unconjucated bilirubin 14.72(±13.28)
µmol/l, Conjucated
bilirubin 10.1( ±8.61) µmol/l, total bilirubin 24.82(±15.8) µmol/l
and Serum Alanine transaminase (ALT) 12.59(±9.59) IU. High prevalence rate of
reduction in liver function was observed among the workers as compared to
control group which might be due to lack of health education. These ill effects
are due to lack of safety measures, poor hygiene and lack of basic health
awareness. Impairing of liver function among spray painters can be reduced by
arranging health awareness programs.
